Cart
sales@molnova.com
Estrogen receptor antagonist 8
CAS No. 2889370-92-5
Estrogen receptor antagonist 8( —— )
Catalog No. M37205 CAS No. 2889370-92-5
Estrogen receptor antagonist 8 acts as an estrogen receptor (ER) antagonist with anti-uterine activity and potential anti-tumorigenic activity and can be used to study ovarian dysfunction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 445 | Get Quote |
|
| 5MG | 686 | Get Quote |
|
| 10MG | 938 | Get Quote |
|
| 25MG | 1398 | Get Quote |
|
| 50MG | 1822 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameEstrogen receptor antagonist 8
-
NoteResearch use only, not for human use.
-
Brief DescriptionEstrogen receptor antagonist 8 acts as an estrogen receptor (ER) antagonist with anti-uterine activity and potential anti-tumorigenic activity and can be used to study ovarian dysfunction.
-
DescriptionEstrogen receptor antagonist 8 is a potent ER-antagonist with in vivo anti-uterotrophic potential (EC50 = 4.160 μM).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetEstrogen Receptor/ERR
-
RecptorEstrogen/progestogen Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2889370-92-5
-
Formula Weight427.45
-
Molecular FormulaC25H21N3O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=N(=O)C1=CC=C(C=C1)N2N=C3C=4C=CC(OC)=CC4CCC3=C2C=5C=CC(OC)=CC5
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Mahmoud A Ragab, et al. Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity. Bioorg Chem. 2022 Feb;119:105554.?
molnova catalog
related products
-
WAY-204688
WAY-204688 is a selective and orally active estrogen receptor inhibitor of NF-κB transcriptional activity (IC50 = 122 nM in HAECT-1 cells).
-
H3B-5942
H3B-5942 is an orally available, selective estrogen receptor covalent antagonist (SERCA), demonstrates potent ERαantagonist activity in vitro and in vivo.
-
Serba-2
Serba-2 is an agonist of benzopyran selective estrogen receptor beta.
